Student Education Repository (மாணவர்கள் கல்விக் களஞ்சியம்): Today (January 9, 1922) is the birthday of Nobel laureate Har Gobind Khorana, who researched the genetic code and their role in the synthetic production of protein.

Saturday, January 9, 2021

Today (January 9, 1922) is the birthday of Nobel laureate Har Gobind Khorana, who researched the genetic code and their role in the synthetic production of protein.

Today (January 9, 1922) is the birthday of Nobel laureate Har Gobind Khorana, who researched the genetic code and its role in the synthetic production of protein.

Har Gobind Khorana was born on January 9, 1922, in the village of Raipur, Punjab, the fifth child. His father worked as a tax collector in the village. Although his family grew up in poverty, his father was keen on educating his children. In his village of about 100 families, only the family of Khorana was literate. Khorana's primary education began at a village school under a tree. From an early age, he excelled in his studies. He attended DAV High School in Multan, West Bengal. He was fascinated by the author 'Rathanlal'. He completed his schooling and continued his studies at Punjab University, Lahore. Passed first class in B.Sc degree. He completed his postgraduate degree in Chemistry in 1945 under the supervision of Madan Singh, a professor and eminent researcher here.

Khorana received a scholarship from the Government of India in 1945 to study at the University of Liverpool in the United Kingdom and receive a doctorate. Here 'Roger JS Peer' acted as his guide. After coming here he started following the western cultural way. In 1948-49 he continued his research at the Federal Institute of Technology in Switzerland. Professor Vladimir Brylak also guided his progress by developing a scientific interest, involvement in the work, and the development of corresponding skills. Khorana went to Canada in 1952, where he befriended Esther Elizabeth Sipler, the daughter of a Swiss parliamentarian. Then she married him. The couple had two daughters and a son. At the end of 1949, India returned to India. After months of unemployment in India, Khorana returned to the UK with the intention of further research.

Dr GW Kenner co-authored the study with Nobel Prize-winning scientist Sir Alexander Todd. Involved in the study of proteins and nucleic acids in 1950-52. In 1952 he became a researcher at the British Columbia Laboratory at the invitation of Dr Gordon M. Shrum. Despite Dr Shram's encouragement, Dr Jack Kemble undertook research on phosphate esters and nucleic acids. Although many others with him contributed to the study, 'Dr. Gordon M. Tener 'was a great guide to the team's research progress. In 1960 he joined the Institute for the Study of Enzymes at the University of Wisconsin and continued all research. He was then granted citizenship in the United States. From 1962 to 1970 he was a professor, professor of biochemistry and deputy director of the institute.

Pin on DNA-types

Dna GIF - Find on GIFER

In 1959, Khorana developed a chemical called coenzyme-A, which is essential for certain processes in the human body. The following year, Curana travelled to the United States to work with his Nobel Prize-winning fellow researcher, Marshall Norenberg, at the University of Wisconsin Enzyme Research Institute. There they discovered that some of the inherited diseases could be cured as a result of their research. The Nobel Prize in Physiology or Medicine was awarded in 1968 to Khorana, Norenberg and Holley for their research on genetic code and their role in the synthetic production of protein. Khorana was later awarded the title of Professor of Biology and Chemistry at the Massachusetts Institute of Technology in 1970. There, his work on the genetic code became world-famous. Scientists at the University of Cambridge have already studied the structure of Escherichia coli bacteria in the gut of humans and animals.

File:The Structure of DNA GIF.gif - Wikimedia Commons

Khorana and his team were involved in the genetic development of the microbe. Gradually, they synthesized about 207 genes of the bacterium. Then in August 1976, the synthetic gene was inserted into the Escherichia coli bacterium, which acted similarly to the natural gene. The world marvelled at this achievement. It took Khorana and the 24 assistants on his team about nine years to successfully complete their studies. Even with the Nobel Prize, Corona has won many more prizes and awards. In 1969 he was awarded the Padma Bhushan. In 1968, he was awarded the 'Distinguished Service Award' by the Wattumul organization based in Honolulu, Hawaii. In 1971 it was awarded the American Academy of Achievement Award by the American Academy of Philadelphia in Pennsylvania. In 1972, the Bose Company 'J.C. Presented Bose 'medal.

An Edited Google Doodle and a Genetics Mini-Mystery – Concord Consortium

He was awarded the Willard Gibbs Medal by the Chicago Division of American Chemistry for 1973-74. Corona has received awards such as the 'Kirchner Organization International Award', the 'Louisa Cross Horwitz Prize', and the 'Albert Lasker Prize for Basic Medical Research. He has been recognized as a Fellow of the American National Academy of Sciences and the American Academy of Sciences. In 1971 he was accepted as a foreign member of the Russian Academy of Sciences. In 1974 he was appointed an Honorary Research Fellow of the Indian Chemical Society. He was appointed a member of the scientific governing board of the Scripps Research Institute.

Madison, Wisconsin, High Technology, and the Indo-US Science and Technology Organization co-founded the Khorana Program in 2007. It was created in the name of Corona to continue research. It is attended by many scientists, businessmen and social activists from India and the United States. Work is ongoing to improve the research mindset of graduate, postgraduate and postgraduate students, with an emphasis on rural development, food security, etc. In 2009, Corona was invited to the event and was honoured. Har Gobind Khorana, the winner of the Nobel Prize for his research into the synthetic production of protein, passed away on November 9, 2011, in Concord, Massachusetts, USA, at the age of 89.

Source By: Wikipedia

Information: Ramesh, Assistant Professor of Physics, Nehru Memorial College, Puthanampatti, Trichy.